Two adults and three children were treated by paramedics after a fire in a block of high rise flats in Kingsland Road.
Firefighters were called to Dorset Court at 9.25pm last night and found the fire was already out on their arrival.
One adult was treated for burns and the other adult and children were treated for smoke inhalation.
Four crews attended the scene and used an aerial platform to ensure the flats were safe.
The patients were left in the care of the ambulance service.