Cafe Welcome will be held in St Paul's Church, New Town Street, Luton, every Wednesday, from 9am till 12noon.
Revd Kate Lomax, Associate Vicar, said: "We hope that the cafe will provide a space for the community to come together and a place where people can meet new friends and get to know others living in their local area.
"As a church we wanted to do something to help the local community.
"We wanted to do something to tackle the issues of loneliness and isolation that people face and provide a space where people of all ages can come together and get to know their neighbours.
"We also wanted to support families where finances are tight with a cafe where their children can enjoy a healthy snack and drink free of charge.
"As a church, we are keen for the community to know we are not just a place that is open on a Sunday, but somewhere where you can find a warm welcome during the week too."