Hatters to host Owls in FA Youth Cup
The Hatters have faced the Owls in this competition before, when the youngsters, then managed by Paul Driver, were beaten 4-0 at Hillsborough back in December 2016.
Holders Liverpool face a trip to face Tottenham Hotspur, with games scheduled to be completed before Saturday 14 December.
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Hide AdFull draw: Manchester City v Swansea City; Shrewsbury Town or Sunderland v Birmingham City; Cardiff City v Ipswich Town or Exeter City; Cheltenham Town or Portsmouth v Arsenal; Stevenage or Brentwood Town or Peterborough United v Aston Villa; Carlisle United or Bradford City v Stoke City; Manchester United v Lincoln City or Wrexham; Wigan Athletic v Croydon or Bath City; Preston North End v Bristol City; Sheffield United v Hanworth Villa or AFC Wimbledon; Fulham v South Shields or Hartlepool United; Norwich City v Newcastle United; Bristol Rovers v Southampton; Luton Town v Sheffield Wednesday; Blackburn Rovers v Uxbridge or Newport County; Chelsea v Huddersfield Town; Mansfield Town or Rotherham United v Queens Park Rangers; Reading v Crystal Palace; Wolverhampton Wanderers v Nottingham Forest; Fleetwood Town v Watford; Brighton & Hove Albion v Leicester City; Middlesbrough v Dulwich Hamlet or Forest Green Rovers; Tottenham Hotspur v Liverpool; Leeds United v Hull City; Burton Albion or Bolton Wanderers v Millwall; Crewe Alexandra or Grimsby Town v Barnsley; Colchester United or Oxford United v Ware or Maidenhead United; AFC Bournemouth v Barnet or Cambridge United; Curzon Ashton or Oldham Athletic v Burnley; West Ham United v Charlton Athletic; Derby County v Everton; West Bromwich Albion v Scunthorpe United or Morpeth Town.